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Synthesis and Biological Evaluation of Flavonoid‐Cinnamic Acid Amide Hybrids with Distinct Activity against Neurodegeneration in Vitro and in Vivo

Flavonoids are polyphenolic natural products and have shown significant potential as disease‐modifying agents against neurodegenerative disorders like Alzheimer's disease (AD), with activities even in vivo. Hybridization of the natural products taxifolin and silibinin with cinnamic acid led to...

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Detalles Bibliográficos
Autores principales: Hofmann, Julian, Spatz, Philipp, Walther, Rasmus, Gutmann, Marcus, Maurice, Tangui, Decker, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400986/
https://www.ncbi.nlm.nih.gov/pubmed/35621167
http://dx.doi.org/10.1002/chem.202200786