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Synthesis and Biological Evaluation of Flavonoid‐Cinnamic Acid Amide Hybrids with Distinct Activity against Neurodegeneration in Vitro and in Vivo
Flavonoids are polyphenolic natural products and have shown significant potential as disease‐modifying agents against neurodegenerative disorders like Alzheimer's disease (AD), with activities even in vivo. Hybridization of the natural products taxifolin and silibinin with cinnamic acid led to...
Autores principales: | Hofmann, Julian, Spatz, Philipp, Walther, Rasmus, Gutmann, Marcus, Maurice, Tangui, Decker, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400986/ https://www.ncbi.nlm.nih.gov/pubmed/35621167 http://dx.doi.org/10.1002/chem.202200786 |
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