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Investigating the Role of Sulfate Groups for the Binding of Gd(3+) Ions to Glycosaminoglycans with NMR Relaxometry

Glycosaminoglycans (GAGs) are highly negatively charged macromolecules with a large cation binding capacity, but their interaction potential with exogeneous Gd(3+) ions is under‐investigated. These might be released from chelates used as Gadolinium‐based contrast agents (GBCAs) for clinical MR imagi...

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Detalles Bibliográficos
Autores principales: Werner, Patrick, Schuenke, Patrick, Krylova, Oxana, Nikolenko, Heike, Taupitz, Matthias, Schröder, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400987/
https://www.ncbi.nlm.nih.gov/pubmed/35451227
http://dx.doi.org/10.1002/cmdc.202100764