3,4,5‐Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers

The synthesis of five new multivalent derivatives of a trihydroxypiperidine iminosugar was accomplished through copper catalyzed alkyne‐azide cycloaddition (CuAAC) reaction of an azido ending piperidine and several propargylated scaffolds. The resulting multivalent architectures were assayed as inhi...

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Detalles Bibliográficos
Autores principales: Vanni, Costanza, Clemente, Francesca, Paoli, Paolo, Morrone, Amelia, Matassini, Camilla, Goti, Andrea, Cardona, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400994/
https://www.ncbi.nlm.nih.gov/pubmed/35322924
http://dx.doi.org/10.1002/cbic.202200077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400994/
https://www.ncbi.nlm.nih.gov/pubmed/35322924
http://dx.doi.org/10.1002/cbic.202200077

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