Advances towards Cell‐Specific Gene Transfection: A Small‐Molecule Approach Allows Order‐of‐Magnitude Selectivity

A transfection vector that can home in on tumors is reported. Whereas previous vectors that allow moderately cell selective gene transfection used larger systems, this small‐molecule approach paved the way for precise structure‐activity relationship optimization. For this, biotin, which mediates cel...

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Detalles Bibliográficos
Autores principales: Dirksmeyer, Thies, Stahl, Paul, Vallet, Cecilia, Knauer, Shirley, Giese, Michael, Schmuck, Carsten, Hirschhäuser, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401007/
https://www.ncbi.nlm.nih.gov/pubmed/35604769
http://dx.doi.org/10.1002/chem.202104618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401007/
https://www.ncbi.nlm.nih.gov/pubmed/35604769
http://dx.doi.org/10.1002/chem.202104618

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