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A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C(α)‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase

Methyl‐coenzyme M reductase, which is responsible for the production of the greenhouse gas methane during biological methane formation, carries several unique posttranslational amino acid modifications, including a 2‐(S)‐methylglutamine. The enzyme responsible for the C(α)‐methylation of this glutam...

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Detalles Bibliográficos
Autores principales: Gagsteiger, Jana, Jahn, Sören, Heidinger, Lorenz, Gericke, Lukas, Andexer, Jennifer N., Friedrich, Thorsten, Loenarz, Christoph, Layer, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401015/
https://www.ncbi.nlm.nih.gov/pubmed/35638156
http://dx.doi.org/10.1002/anie.202204198