Total Synthesis of Parameritannin A2, a Branched Epicatechin Tetramer with Two Double Linkages

The first total synthesis of parameritannin A2 (1), a branched epicatechin (EC) tetramer is reported. The “phloroglucinol trick” was used to circumvent two synthetic issues encountered when assembling four EC units, namely, the steric constraint and the formation of the C4−C6 interflavan linkage. As...

Descripción completa

Detalles Bibliográficos
Autores principales: Betkekar, Vipul V., Suzuki, Keisuke, Ohmori, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401032/
https://www.ncbi.nlm.nih.gov/pubmed/35534438
http://dx.doi.org/10.1002/anie.202205106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401032/
https://www.ncbi.nlm.nih.gov/pubmed/35534438
http://dx.doi.org/10.1002/anie.202205106

Ejemplares similares