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A Photoswitchable Ligand Targeting the β(1)‐Adrenoceptor Enables Light‐Control of the Cardiac Rhythm
Catecholamine‐triggered β‐adrenoceptor (β‐AR) signaling is essential for the correct functioning of the heart. Although both β(1)‐ and β(2)‐AR subtypes are expressed in cardiomyocytes, drugs selectively targeting β(1)‐AR have proven this receptor as the main target for the therapeutic effects of bet...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401038/ https://www.ncbi.nlm.nih.gov/pubmed/35608051 http://dx.doi.org/10.1002/anie.202203449 |