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A Photoswitchable Ligand Targeting the β(1)‐Adrenoceptor Enables Light‐Control of the Cardiac Rhythm

Catecholamine‐triggered β‐adrenoceptor (β‐AR) signaling is essential for the correct functioning of the heart. Although both β(1)‐ and β(2)‐AR subtypes are expressed in cardiomyocytes, drugs selectively targeting β(1)‐AR have proven this receptor as the main target for the therapeutic effects of bet...

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Detalles Bibliográficos
Autores principales: Duran‐Corbera, Anna, Faria, Melissa, Ma, Yuanyuan, Prats, Eva, Dias, André, Catena, Juanlo, Martinez, Karen L., Raldua, Demetrio, Llebaria, Amadeu, Rovira, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401038/
https://www.ncbi.nlm.nih.gov/pubmed/35608051
http://dx.doi.org/10.1002/anie.202203449

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