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Spectroscopic and in vitro Investigations of Fe(2+)/α‐Ketoglutarate‐Dependent Enzymes Involved in Nucleic Acid Repair and Modification
The activation of molecular oxygen for the highly selective functionalization and repair of DNA and RNA nucleobases is achieved by α‐ketoglutarate (α‐KG)/iron‐dependent dioxygenases. Of special interest are the human homologues AlkBH of Escherichia coli EcAlkB and ten‐eleven translocation (TET) enzy...
Autores principales: | Schmidl, David, Lindlar né Jonasson, Niko S. W., Menke, Annika, Schneider, Sabine, Daumann, Lena J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401043/ https://www.ncbi.nlm.nih.gov/pubmed/35040547 http://dx.doi.org/10.1002/cbic.202100605 |
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