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A Clickable Bioorthogonal Sydnone‐Aglycone for the Facile Preparation of a Core 1 O‐Glycan‐Array

Protein‐O‐glycosylation has been shown to be essential for many biological processes. However, determining the exact relationship between O‐glycan structures and their biological activity remains challenging. Here we report that, unlike azides, sydnones can be incorporated as an aglycon into core 1...

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Detalles Bibliográficos
Autores principales: Chinoy, Zoeisha S., Moremen, Kelley W., Friscourt, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401066/
https://www.ncbi.nlm.nih.gov/pubmed/36035814
http://dx.doi.org/10.1002/ejoc.202200271