Enantioselective (8+3) Cycloadditions by Activation of Donor–Acceptor Cyclopropanes Employing Chiral Brønsted Base Catalysis

A novel enantioselective (8+3) cycloaddition between donor–acceptor cyclopropanes and heptafulvenoids catalysed by a chiral bifunctional Brønsted base is described. Importantly, the reaction, which leverages an anionic activation strategy, is divergent from prototypical Lewis‐acid activation protoco...

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Detalles Bibliográficos
Autores principales: McLeod, David A., Thøgersen, Mathias Kirk, Barløse, Casper Larsen, Skipper, Mette Louise, Obregón, Erlaitz Basabe, Jørgensen, Karl Anker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401081/
https://www.ncbi.nlm.nih.gov/pubmed/35580010
http://dx.doi.org/10.1002/anie.202206096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401081/
https://www.ncbi.nlm.nih.gov/pubmed/35580010
http://dx.doi.org/10.1002/anie.202206096

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