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Interferon-γ augments GABA release in the developing neocortex via nitric oxide synthase/soluble guanylate cyclase and constrains network activity

Interferon-γ (IFN-γ), a cytokine with neuromodulatory properties, has been shown to enhance inhibitory transmission. Because early inhibitory neurotransmission sculpts functional neuronal circuits, its developmental alteration may have grave consequences. Here, we investigated the acute effects of I...

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Detalles Bibliográficos
Autores principales: Döhne, Noah, Falck, Alice, Janach, Gabriel M. S., Byvaltcev, Egor, Strauss, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401097/
https://www.ncbi.nlm.nih.gov/pubmed/36035261
http://dx.doi.org/10.3389/fncel.2022.913299