Knockdown of CD146 promotes endothelial-to-mesenchymal transition via Wnt/β-catenin pathway

PURPOSE: Cardiac fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) proteins and leads to the maladaptive changes in myocardium. Endothelial cells (ECs) undergoing mesenchymal transition contributes to the occurrence and development of cardiac fibrosis. CD146 is an a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhao-Yu, Zhai, Chao, Yang, Xue-Yuan, Li, Hai-Bing, Wu, Li-Ling, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401105/
https://www.ncbi.nlm.nih.gov/pubmed/36001597
http://dx.doi.org/10.1371/journal.pone.0273542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401105/
https://www.ncbi.nlm.nih.gov/pubmed/36001597
http://dx.doi.org/10.1371/journal.pone.0273542

Ejemplares similares