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Knockdown of CD146 promotes endothelial-to-mesenchymal transition via Wnt/β-catenin pathway
PURPOSE: Cardiac fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) proteins and leads to the maladaptive changes in myocardium. Endothelial cells (ECs) undergoing mesenchymal transition contributes to the occurrence and development of cardiac fibrosis. CD146 is an a...
Autores principales: | Zhang, Zhao-Yu, Zhai, Chao, Yang, Xue-Yuan, Li, Hai-Bing, Wu, Li-Ling, Li, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401105/ https://www.ncbi.nlm.nih.gov/pubmed/36001597 http://dx.doi.org/10.1371/journal.pone.0273542 |
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