The splenic T cell receptor repertoire during an immune response against a complex antigen: Expanding private clones accumulate in the high and low copy number region

Large cellular antigens comprise a variety of different epitopes leading to a T cell response of extreme diversity. Therefore, tracking such a response by next generation sequencing of the T cell receptor (TCR) in order to identify common TCR properties among the expanding T cells represents an enor...

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Detalles Bibliográficos
Autores principales: Meinhardt, Martin, Tune, Cornelia, Schierloh, Lisa-Kristin, Schampel, Andrea, Pagel, René, Westermann, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401120/
https://www.ncbi.nlm.nih.gov/pubmed/36001559
http://dx.doi.org/10.1371/journal.pone.0273264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401120/
https://www.ncbi.nlm.nih.gov/pubmed/36001559
http://dx.doi.org/10.1371/journal.pone.0273264

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