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Distinct translatome changes in specific neural populations precede electroencephalographic changes in prion-infected mice

Selective vulnerability is an enigmatic feature of neurodegenerative diseases (NDs), whereby a widely expressed protein causes lesions in specific cell types and brain regions. Using the RiboTag method in mice, translational responses of five neural subtypes to acquired prion disease (PrD) were meas...

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Detalles Bibliográficos
Autores principales: Kaczmarczyk, Lech, Schleif, Melvin, Dittrich, Lars, Williams, Rhiannan H., Koderman, Maruša, Bansal, Vikas, Rajput, Ashish, Schulte, Theresa, Jonson, Maria, Krost, Clemens, Testaquadra, Fabio J., Bonn, Stefan, Jackson, Walker S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401167/
https://www.ncbi.nlm.nih.gov/pubmed/35960762
http://dx.doi.org/10.1371/journal.ppat.1010747