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STING-pathway modulation to enhance the immunogenicity of adenoviral-vectored vaccines

Traditional chemical adjuvants remain a practical means of enhancing the immunogenicity of vaccines. Nevertheless, it is recognized that increasing the immunogenicity of viral vectors is challenging. Recently, STING ligands have been shown to enhance the efficacy of different vaccine platforms, but...

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Detalles Bibliográficos
Autores principales: Padron-Regalado, Eriko, Ulaszewska, Marta, Douglas, Alexander D., Hill, Adrian V. S., Spencer, Alexandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401198/
https://www.ncbi.nlm.nih.gov/pubmed/36002507
http://dx.doi.org/10.1038/s41598-022-18750-3