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Reduced diversity of intestinal T-cell receptor repertoire in patients with Crohn’s disease

BACKGROUND: The intestinal microenvironment directly determines the human T-cell receptor (TCR) repertoire. Despite its extreme diversity, TCR repertoire analysis may provide a better understanding of the immune system in patients with inflammatory bowel disease. METHODS: To investigate TCR repertoi...

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Detalles Bibliográficos
Autores principales: Hong, Sung Noh, Park, Joo-Young, Yang, So-Yun, Lee, Chansu, Kim, Young-Ho, Joung, Je-Gun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401206/
https://www.ncbi.nlm.nih.gov/pubmed/36034703
http://dx.doi.org/10.3389/fcimb.2022.932373