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T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas

PURPOSE: Gliomas are intrinsic brain tumors with a high degree of constitutive and acquired resistance to standard therapeutic modalities such as radiotherapy and alkylating chemotherapy. Glioma subtypes are recognized by characteristic mutations. Some of these characteristic mutations have shown to...

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Detalles Bibliográficos
Autores principales: Kilian, Michael, Friedrich, Mirco, Sanghvi, Khwab, Green, Edward, Pusch, Stefan, Kawauchi, Daisuke, Löwer, Martin, Sonner, Jana K., Krämer, Christopher, Zaman, Julia, Jung, Stefanie, Breckwoldt, Michael O., Willimsky, Gerald, Eichmüller, Stefan B., von Deimling, Andreas, Wick, Wolfgang, Sahm, Felix, Platten, Michael, Bunse, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401455/
https://www.ncbi.nlm.nih.gov/pubmed/34782365
http://dx.doi.org/10.1158/1078-0432.CCR-21-1881