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Longitudinal Copy-Number Alteration Analysis in Plasma Cell-Free DNA of Neuroendocrine Neoplasms is a Novel Specific Biomarker for Diagnosis, Prognosis, and Follow-up

PURPOSE: As noninvasive biomarkers are an important unmet need for neuroendocrine neoplasms (NEN), biomarker potential of genome-wide molecular profiling of plasma cell-free DNA (cfDNA) was prospectively studied in patients with NEN. EXPERIMENTAL DESIGN: Longitudinal plasma samples were collected fr...

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Detalles Bibliográficos
Autores principales: Boons, Gitta, Vandamme, Timon, Mariën, Laura, Lybaert, Willem, Roeyen, Geert, Rondou, Tim, Papadimitriou, Konstantinos, Janssens, Katrien, Op de Beeck, Bart, Simoens, Marc, Demey, Wim, Dero, Isabel, Van Camp, Guy, Peeters, Marc, Op de Beeck, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401546/
https://www.ncbi.nlm.nih.gov/pubmed/34759042
http://dx.doi.org/10.1158/1078-0432.CCR-21-2291