Preparation of Distant Quaternary Carbon Stereocenters by Double Selective Ring‐Opening of 1,1‐Biscyclopropyl Methanol Derivatives

The diastereoselective double carbometalation reaction of cyclopropenes provides, in a single‐pot operation, two ω‐ene‐[1,1]‐bicyclopropyl ester derivatives. One regioisomer then undergoes a Pd‐catalyzed addition of aryl iodide to provide skipped dienes possessing several distant stereocenters inclu...

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Detalles Bibliográficos
Autores principales: Siddaraju, Yogesh, Sabbatani, Juliette, Cohen, Anthony, Marek, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401570/
https://www.ncbi.nlm.nih.gov/pubmed/35521738
http://dx.doi.org/10.1002/anie.202203652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401570/
https://www.ncbi.nlm.nih.gov/pubmed/35521738
http://dx.doi.org/10.1002/anie.202203652

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