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A Practical and Scalable Approach to Fluoro‐Substituted Bicyclo[1.1.1]pentanes
After more than 20 years of trials, a practical scalable approach to fluoro‐substituted bicyclo[1.1.1]pentanes (F‐BCPs) has been developed. The physicochemical properties of the F‐BCPs have been studied, and the core was incorporated into the structure of the anti‐inflammatory drug Flurbiprofen in p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401599/ https://www.ncbi.nlm.nih.gov/pubmed/35638404 http://dx.doi.org/10.1002/anie.202205103 |