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A Practical and Scalable Approach to Fluoro‐Substituted Bicyclo[1.1.1]pentanes
After more than 20 years of trials, a practical scalable approach to fluoro‐substituted bicyclo[1.1.1]pentanes (F‐BCPs) has been developed. The physicochemical properties of the F‐BCPs have been studied, and the core was incorporated into the structure of the anti‐inflammatory drug Flurbiprofen in p...
Autores principales: | Bychek, Roman, Mykhailiuk, Pavel K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401599/ https://www.ncbi.nlm.nih.gov/pubmed/35638404 http://dx.doi.org/10.1002/anie.202205103 |
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