Comparison of replicating and nonreplicating vaccines against SARS-CoV-2

Most gene-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are nonreplicating vectors. They deliver the gene or messenger RNA to the cell to express the spike protein but do not replicate to amplify antigen production. This study tested the utility of replication in a vacc...

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Detalles Bibliográficos
Autores principales: Mudrick, Haley E., Massey, Shane, McGlinch, Erin B., Parrett, Brian J., Hemsath, Jack R., Barry, Mary E., Rubin, Jeffrey D., Uzendu, Chisom, Hansen, Michael J., Erskine, Courtney L., Van Keulen, Virginia P., Drelich, Aleksandra, Panos, Joseph A., Fida, Madiha, Suh, Gina A., Peikert, Tobias, Block, Matthew S., Tseng, Chien-Te Kent, Olivier, Gloria R., Barry, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401629/
https://www.ncbi.nlm.nih.gov/pubmed/36001674
http://dx.doi.org/10.1126/sciadv.abm8563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401629/
https://www.ncbi.nlm.nih.gov/pubmed/36001674
http://dx.doi.org/10.1126/sciadv.abm8563

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