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Comparison of replicating and nonreplicating vaccines against SARS-CoV-2
Most gene-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are nonreplicating vectors. They deliver the gene or messenger RNA to the cell to express the spike protein but do not replicate to amplify antigen production. This study tested the utility of replication in a vacc...
Autores principales: | Mudrick, Haley E., Massey, Shane, McGlinch, Erin B., Parrett, Brian J., Hemsath, Jack R., Barry, Mary E., Rubin, Jeffrey D., Uzendu, Chisom, Hansen, Michael J., Erskine, Courtney L., Van Keulen, Virginia P., Drelich, Aleksandra, Panos, Joseph A., Fida, Madiha, Suh, Gina A., Peikert, Tobias, Block, Matthew S., Tseng, Chien-Te Kent, Olivier, Gloria R., Barry, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401629/ https://www.ncbi.nlm.nih.gov/pubmed/36001674 http://dx.doi.org/10.1126/sciadv.abm8563 |
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