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SMAD4 and TGFβ are architects of inverse genetic programs during fate determination of antiviral CTLs

Transforming growth factor β (TGFβ) is an important differentiation factor for cytotoxic T lymphocytes (CTLs) and alters the expression levels of several of homing receptors during infection. SMAD4 is part of the canonical signaling network used by members of the transforming growth factor family. F...

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Detalles Bibliográficos
Autores principales: Chandiran, Karthik, Suarez-Ramirez, Jenny E, Hu, Yinghong, Jellison, Evan R, Ugur, Zeynep, Low, Jun Siong, McDonald, Bryan, Kaech, Susan M, Cauley, Linda S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402230/
https://www.ncbi.nlm.nih.gov/pubmed/35942952
http://dx.doi.org/10.7554/eLife.76457