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Mechanism of the cadherin–catenin F-actin catch bond interaction

Mechanotransduction at cell–cell adhesions is crucial for the structural integrity, organization, and morphogenesis of epithelia. At cell–cell junctions, ternary E-cadherin/β-catenin/αE-catenin complexes sense and transmit mechanical load by binding to F-actin. The interaction with F-actin, describe...

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Detalles Bibliográficos
Autores principales: Wang, Amy, Dunn, Alexander R, Weis, William I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402232/
https://www.ncbi.nlm.nih.gov/pubmed/35913118
http://dx.doi.org/10.7554/eLife.80130