Cargando…

Mechanism of the cadherin–catenin F-actin catch bond interaction

Mechanotransduction at cell–cell adhesions is crucial for the structural integrity, organization, and morphogenesis of epithelia. At cell–cell junctions, ternary E-cadherin/β-catenin/αE-catenin complexes sense and transmit mechanical load by binding to F-actin. The interaction with F-actin, describe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Amy, Dunn, Alexander R, Weis, William I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402232/ https://www.ncbi.nlm.nih.gov/pubmed/35913118 http://dx.doi.org/10.7554/eLife.80130

Ejemplares similares

Structural basis of αE-catenin–F-actin catch bond behavior
por: Xu, Xiao-Ping, et al.
Publicado: (2020)

Unraveling the mechanism of the cadherin-catenin-actin catch bond
por: Adhikari, Shishir, et al.
Publicado: (2018)

The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin
por: Owen, Leanna M., et al.
Publicado: (2022)

The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates
por: Mickolajczyk, Keith J, et al.
Publicado: (2022)

Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction
por: Kan, Wei, et al.
Publicado: (2020)

Cadherin clusters stabilized by a combination of specific and nonspecific cis-interactions
por: Thompson, Connor J, et al.
Publicado: (2020)

Gating mechanisms during actin filament elongation by formins
por: Aydin, Fikret, et al.
Publicado: (2018)

Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity
por: Gurel, Pinar S, et al.
Publicado: (2017)

pH-dependent 11° F(1)F(O) ATP synthase sub-steps reveal insight into the F(O) torque generating mechanism
por: Yanagisawa, Seiga, et al.
Publicado: (2021)

The mother of all actins?
por: Merino, Felipe, et al.
Publicado: (2016)

Structural insights into SETD3-mediated histidine methylation on β-actin
por: Guo, Qiong, et al.
Publicado: (2019)

Symmetry breaking in reconstituted actin cortices
por: Abu Shah, Enas, et al.
Publicado: (2014)

Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions
por: Sekhar, Ashok, et al.
Publicado: (2018)

Tuning myosin-driven sorting on cellular actin networks
por: Hariadi, Rizal F, et al.
Publicado: (2015)

Side-binding proteins modulate actin filament dynamics
por: Crevenna, Alvaro H, et al.
Publicado: (2015)

Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4
por: Nicoludis, John M, et al.
Publicado: (2016)

Myosin motors fragment and compact membrane-bound actin filaments
por: Vogel, Sven K, et al.
Publicado: (2013)

Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction
por: Subramanian, Subu, et al.
Publicado: (2021)

Molecular pathology of the R117H cystic fibrosis mutation is explained by loss of a hydrogen bond
por: Simon, Márton A, et al.
Publicado: (2021)

Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
por: Liu, Haiyang, et al.
Publicado: (2016)

Crenactin forms actin-like double helical filaments regulated by arcadin-2
por: Izoré, Thierry, et al.
Publicado: (2016)

Structures of topoisomerase V in complex with DNA reveal unusual DNA-binding mode and novel relaxation mechanism
por: Osterman, Amy, et al.
Publicado: (2022)

A lipid bound actin meshwork organizes liquid phase separation in model membranes
por: Honigmann, Alf, et al.
Publicado: (2014)

Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes
por: Pylypenko, Olena, et al.
Publicado: (2016)

Competition between Tropomyosin, Fimbrin, and ADF/Cofilin drives their sorting to distinct actin filament networks
por: Christensen, Jenna R, et al.
Publicado: (2017)

Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes
por: Huber, Stefan T, et al.
Publicado: (2022)

Mechanism of substrate binding and transport in BASS transporters
por: Becker, Patrick, et al.
Publicado: (2023)

Protein-mediated RNA folding governs sequence-specific interactions between rotavirus genome segments
por: Borodavka, Alexander, et al.
Publicado: (2017)

Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F
por: Alvadia, Carolina, et al.
Publicado: (2019)

Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction
por: Wang, Lan, et al.
Publicado: (2020)

A new insight into RecA filament regulation by RecX from the analysis of conformation-specific interactions
por: Alekseev, Aleksandr, et al.
Publicado: (2022)

Cannabidiol interactions with voltage-gated sodium channels
por: Sait, Lily Goodyer, et al.
Publicado: (2020)

Same structure, different mechanisms?
por: Tsai, Francis TF, et al.
Publicado: (2020)

Single-molecule force spectroscopy of protein-membrane interactions
por: Ma, Lu, et al.
Publicado: (2017)

Mechanical force induces mitochondrial fission
por: Helle, Sebastian Carsten Johannes, et al.
Publicado: (2017)

Aromatic interactions with membrane modulate human BK channel activation
por: Yazdani, Mahdieh, et al.
Publicado: (2020)

Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner
por: Lowe, Alan R, et al.
Publicado: (2015)

Bovine F(1)F(o) ATP synthase monomers bend the lipid bilayer in 2D membrane crystals
por: Jiko, Chimari, et al.
Publicado: (2015)

The mechanism of variability in transcription start site selection
por: Yu, Libing, et al.
Publicado: (2017)

DNA translocation mechanism of an XPD family helicase
por: Cheng, Kaiying, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5vj17gme6oei6l8feeos2ui0u6