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Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A(2B)AR signaling in intestinal epithelial cells

Intestinal nematode parasites can cross the epithelial barrier, causing tissue damage and release of danger-associated molecular patterns (DAMPs) that may promote host protective type 2 immunity. We investigate whether adenosine binding to the A(2B) adenosine receptor (A(2B)AR) on intestinal epithel...

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Detalles Bibliográficos
Autores principales: El-Naccache, Darine W., Chen, Fei, Palma, Mark J., Lemenze, Alexander, Fischer, Matthew A., Wu, Wenhui, Mishra, Pankaj K., Eltzschig, Holger K., Robson, Simon C., Di Virgilio, Francesco, Yap, George S., Edelblum, Karen L., Haskó, György, Gause, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402265/
https://www.ncbi.nlm.nih.gov/pubmed/35926464
http://dx.doi.org/10.1016/j.celrep.2022.111150