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Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A(2B)AR signaling in intestinal epithelial cells
Intestinal nematode parasites can cross the epithelial barrier, causing tissue damage and release of danger-associated molecular patterns (DAMPs) that may promote host protective type 2 immunity. We investigate whether adenosine binding to the A(2B) adenosine receptor (A(2B)AR) on intestinal epithel...
Autores principales: | El-Naccache, Darine W., Chen, Fei, Palma, Mark J., Lemenze, Alexander, Fischer, Matthew A., Wu, Wenhui, Mishra, Pankaj K., Eltzschig, Holger K., Robson, Simon C., Di Virgilio, Francesco, Yap, George S., Edelblum, Karen L., Haskó, György, Gause, William C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402265/ https://www.ncbi.nlm.nih.gov/pubmed/35926464 http://dx.doi.org/10.1016/j.celrep.2022.111150 |
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