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Effect of Chaihu Shugan Pills on the Pharmacokinetics of Duloxetine and its Metabolite 4-Hydroxyduloxetine in Beagle Dogs: A Herb-Drug Interaction Study

The effect of Chaihu Shugan pills (CHSG) on the pharmacokinetics of duloxetine and its metabolite 4-hydroxyduloxetine in beagle dogs was investigated by establishing an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method to simultaneously measure the concentrations o...

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Detalles Bibliográficos
Autores principales: Bi, Yun-tian, Kang, Yao-ren, Woshur, Ghulam, Ding, Hao-zhe, Wang, Shan-shan, Qiu, Xiang-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402319/
https://www.ncbi.nlm.nih.gov/pubmed/36034951
http://dx.doi.org/10.1155/2022/2350560