Cryo-EM structure of an active bacterial TIR–STING filament complex

Stimulator of interferon genes (STING) is an antiviral signalling protein that is broadly conserved in both innate immunity in animals and phage defence in prokaryotes(1–4). Activation of STING requires its assembly into an oligomeric filament structure through binding of a cyclic dinucleotide(4–13)...

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Detalles Bibliográficos
Autores principales: Morehouse, Benjamin R., Yip, Matthew C. J., Keszei, Alexander F. A., McNamara-Bordewick, Nora K., Shao, Sichen, Kranzusch, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402430/
https://www.ncbi.nlm.nih.gov/pubmed/35859168
http://dx.doi.org/10.1038/s41586-022-04999-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402430/
https://www.ncbi.nlm.nih.gov/pubmed/35859168
http://dx.doi.org/10.1038/s41586-022-04999-1

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