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Pharmacokinetic Assessment and Treatment Effect of Lusutrombopag in Child–Pugh Class C Patients: Review of Patient Data from Two Clinical Studies and Post-Marketing Surveillance

INTRODUCTION: Patients with thrombocytopenia and chronic liver disease are at increased risk of bleeding during invasive procedures due to low platelet counts. Lusutrombopag, an orally active thrombopoietin receptor agonist, increases platelet count and reduces the need for platelet transfusion in c...

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Detalles Bibliográficos
Autores principales: Flamm, Steven L., Peck-Radosavljevic, Markus, Fukuhara, Takahiro, Bentley, Roy, Katsube, Takayuki, Ochiai, Toshimitsu, Kano, Takeshi, Tsukimura, Eri, Sasaki, Ritsue, Osaki, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402490/
https://www.ncbi.nlm.nih.gov/pubmed/35904722
http://dx.doi.org/10.1007/s12325-022-02237-8