Cargando…
Cdk5 regulates IP3R1-mediated Ca(2+) dynamics and Ca(2+)-mediated cell proliferation
Loss of cyclin-dependent kinase 5 (Cdk5) in the mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs) increases ER–mitochondria tethering and ER Ca(2+) transfer to the mitochondria, subsequently increasing mitochondrial Ca(2+) concentration ([Ca(2+)](mt)). This suggests a role for Cdk5...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402492/ https://www.ncbi.nlm.nih.gov/pubmed/36001172 http://dx.doi.org/10.1007/s00018-022-04515-8 |