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Kinase inhibitors increase individual radiation sensitivity in normal cells of cancer patients

PURPOSE: Kinase inhibitors (KI) are known to increase radiosensitivity, which can lead to increased risk of side effects. Data about interactions of commonly used KI with ionizing radiation on healthy tissue are rare. PATIENTS AND METHODS: Freshly drawn blood samples were analyzed using three-color...

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Detalles Bibliográficos
Autores principales: Jost, Tina, Schuster, Barbara, Heinzerling, Lucie, Weissmann, Thomas, Fietkau, Rainer, Distel, Luitpold V., Hecht, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402507/
https://www.ncbi.nlm.nih.gov/pubmed/35471558
http://dx.doi.org/10.1007/s00066-022-01945-y