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Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells

On glucose restriction, epithelial cells can undergo entosis, a cell-in-cell cannibalistic process, to allow considerable withstanding to this metabolic stress. Thus, we hypothesized that reduced protein glycosylation might participate in the activation of this cell survival pathway. Glucose depriva...

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Detalles Bibliográficos
Autores principales: Hyroššová, Petra, Aragó, Marc, Muñoz-Pinedo, Cristina, Viñals, Francesc, García-Rovés, Pablo M., Escolano, Carmen, Méndez-Lucas, Andrés, Perales, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402552/
https://www.ncbi.nlm.nih.gov/pubmed/36002449
http://dx.doi.org/10.1038/s41419-022-05177-x