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Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex

To eliminate specific or aberrant transcripts, eukaryotes use nuclear RNA-targeting complexes that deliver them to the exosome for degradation. S. pombe MTREC, and its human counterpart PAXT, are key players in this mechanism but inner workings of these complexes are not understood in sufficient det...

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Detalles Bibliográficos
Autores principales: Foucher, Anne-Emmanuelle, Touat-Todeschini, Leila, Juarez-Martinez, Ariadna B., Rakitch, Auriane, Laroussi, Hamida, Karczewski, Claire, Acajjaoui, Samira, Soler-López, Montserrat, Cusack, Stephen, Mackereth, Cameron D., Verdel, André, Kadlec, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402713/
https://www.ncbi.nlm.nih.gov/pubmed/36002457
http://dx.doi.org/10.1038/s41467-022-32542-3