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Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex
To eliminate specific or aberrant transcripts, eukaryotes use nuclear RNA-targeting complexes that deliver them to the exosome for degradation. S. pombe MTREC, and its human counterpart PAXT, are key players in this mechanism but inner workings of these complexes are not understood in sufficient det...
Autores principales: | Foucher, Anne-Emmanuelle, Touat-Todeschini, Leila, Juarez-Martinez, Ariadna B., Rakitch, Auriane, Laroussi, Hamida, Karczewski, Claire, Acajjaoui, Samira, Soler-López, Montserrat, Cusack, Stephen, Mackereth, Cameron D., Verdel, André, Kadlec, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402713/ https://www.ncbi.nlm.nih.gov/pubmed/36002457 http://dx.doi.org/10.1038/s41467-022-32542-3 |
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