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XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis

AIMS: Pancreatic β-cell apoptosis may be involved in the onset and progression of type 2 diabetes mellitus, although its mechanism remains unclear. We previously demonstrated that macrophage-derived interferon (IFN) β induced X-linked inhibitor of apoptosis–associated factor 1 (XAF1) expression in β...

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Detalles Bibliográficos
Autores principales: Nishimura, Yuki, Iwashita, Misaki, Hayashi, Masato, Shinjo, Takanori, Watanabe, Yukari, Zeze, Tatsuro, Yamashita, Akiko, Fukuda, Takao, Sanui, Terukazu, Sano, Tomomi, Asano, Tomoichiro, Nishimura, Fusanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402739/
https://www.ncbi.nlm.nih.gov/pubmed/35829914
http://dx.doi.org/10.1007/s00592-022-01930-y