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Systemic Therapy for Gastrointestinal Stromal Tumor: Current Standards and Emerging Challenges

Gastrointestinal stromal tumor (GIST), though rare, is the most common mesenchymal tumors of the gastrointestinal tract. KIT or PDGFRα mutation plays as an oncogenic driver in the majority of GISTs. Surgical resection is the only curative treatment for localized disease. The discovery of imatinib wi...

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Detalles Bibliográficos
Autores principales: Huang, Wen-Kuan, Wu, Chiao-En, Wang, Shang-Yu, Chang, Ching-Fu, Chou, Wen-Chi, Chen, Jen-Shi, Yeh, Chun-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402763/
https://www.ncbi.nlm.nih.gov/pubmed/35976553
http://dx.doi.org/10.1007/s11864-022-00996-8