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Systemic Therapy for Gastrointestinal Stromal Tumor: Current Standards and Emerging Challenges
Gastrointestinal stromal tumor (GIST), though rare, is the most common mesenchymal tumors of the gastrointestinal tract. KIT or PDGFRα mutation plays as an oncogenic driver in the majority of GISTs. Surgical resection is the only curative treatment for localized disease. The discovery of imatinib wi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402763/ https://www.ncbi.nlm.nih.gov/pubmed/35976553 http://dx.doi.org/10.1007/s11864-022-00996-8 |