Differential Splicing of Skipped Exons Predicts Drug Response in Cancer Cell Lines

Alternative splicing of pre-mRNA transcripts is an important regulatory mechanism that increases the diversity of gene products in eukaryotes. Various studies have linked specific transcript isoforms to altered drug response in cancer; however, few algorithms have incorporated splicing information i...

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Detalles Bibliográficos
Autores principales: Simpson, Edward, Chen, Steven, Reiter, Jill L., Liu, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402787/
https://www.ncbi.nlm.nih.gov/pubmed/33662622
http://dx.doi.org/10.1016/j.gpb.2019.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402787/
https://www.ncbi.nlm.nih.gov/pubmed/33662622
http://dx.doi.org/10.1016/j.gpb.2019.08.003

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