Computational Assessment of Protein–protein Binding Affinity by Reversely Engineering the Energetics in Protein Complexes

The cellular functions of proteins are maintained by forming diverse complexes. The stability of these complexes is quantified by the measurement of binding affinity, and mutations that alter the binding affinity can cause various diseases such as cancer and diabetes. As a result, accurate estimatio...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Su, Zhaoqian, Wu, Yinghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403033/
https://www.ncbi.nlm.nih.gov/pubmed/33838354
http://dx.doi.org/10.1016/j.gpb.2021.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403033/
https://www.ncbi.nlm.nih.gov/pubmed/33838354
http://dx.doi.org/10.1016/j.gpb.2021.03.004

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