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Computational Assessment of Protein–protein Binding Affinity by Reversely Engineering the Energetics in Protein Complexes
The cellular functions of proteins are maintained by forming diverse complexes. The stability of these complexes is quantified by the measurement of binding affinity, and mutations that alter the binding affinity can cause various diseases such as cancer and diabetes. As a result, accurate estimatio...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403033/ https://www.ncbi.nlm.nih.gov/pubmed/33838354 http://dx.doi.org/10.1016/j.gpb.2021.03.004 |