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Simultaneous quantitation of 17 endogenous adrenal corticosteroid hormones in human plasma by UHPLC-MS/MS and their application in congenital adrenal hyperplasia screening

Accurate investigation of adrenal hormone levels plays a vital role in pediatric endocrinology for the detection of steroid-related disorders. This study aims to develop a straightforward, sensitive UHPLC-MS/MS method to quantify 17 endogenous adrenal corticosteroid hormones in human plasma. These h...

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Detalles Bibliográficos
Autores principales: Zhang, Qiaoxuan, Zhan, Min, Wu, Huihui, Feng, Pinning, Jin, Xing, Wan, Zemin, Yan, Jun, Zhang, Pengwei, Ke, Peifeng, Zhuang, Junhua, Zhou, Jiuyao, Han, Liqiao, Huang, Xianzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403142/
https://www.ncbi.nlm.nih.gov/pubmed/36034654
http://dx.doi.org/10.3389/fchem.2022.961660