Multi-gene panel testing increases germline predisposing mutations’ detection in a cohort of breast/ovarian cancer patients from Southern Italy

Breast cancer is the most common neoplasia in females worldwide, about 10% being hereditary/familial and due to DNA variants in cancer-predisposing genes, such as the highly penetrant BRCA1/BRCA2 genes. However, their variants explain up to 25% of the suspected hereditary/familial cases. The availab...

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Detalles Bibliográficos
Autores principales: Nunziato, Marcella, Di Maggio, Federica, Pensabene, Matilde, Esposito, Maria Valeria, Starnone, Flavio, De Angelis, Carmine, Calabrese, Alessandra, D’Aiuto, Massimiliano, Botti, Gerardo, De Placido, Sabino, D’Argenio, Valeria, Salvatore, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403188/
https://www.ncbi.nlm.nih.gov/pubmed/36035419
http://dx.doi.org/10.3389/fmed.2022.894358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403188/
https://www.ncbi.nlm.nih.gov/pubmed/36035419
http://dx.doi.org/10.3389/fmed.2022.894358

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