Inhibiting vascular smooth muscle cell proliferation mediated by osteopontin via regulating gut microbial lipopolysaccharide: A novel mechanism for paeonol in atherosclerosis treatment

Background: Although the gut microbiota is involved in metabolic disease such as atherosclerosis, the underlying mechanism remains elusive. Paeonol (Pae) is a natural phenolic compound isolated from Cortex Moutan, which exhibits anti-atherosclerotic effects. Our previous research demonstrated gut mi...

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Detalles Bibliográficos
Autores principales: Shi, Xiaoyan, Wu, Hongfei, Liu, Yarong, Huang, Hanwen, Liu, Ling, Yang, Yulong, Jiang, Tingting, Zhou, Min, Dai, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403310/
https://www.ncbi.nlm.nih.gov/pubmed/36034838
http://dx.doi.org/10.3389/fphar.2022.936677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403310/
https://www.ncbi.nlm.nih.gov/pubmed/36034838
http://dx.doi.org/10.3389/fphar.2022.936677

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