Surfactant-mediated extraction of capsaicin from Capsicum annuum L. fruit in various solvents

Capsaicin is a valuable compound found in Capsicum annuum. The present study aimed to explore the efficiency of different solvents and surfactants on its extraction by maceration. Ethyl acetate was found to be the best solvent followed by dichloromethane and acetone, respectively. Overall order of efficiency of the solvents used was this: ethyl acetate > dichloromethane > acetone > glycerol > acetonitrile > methanol > acetic acid > toluene. Extractability of ethyl acetate for capsaicin remained unaffected by the surfactants. Tween-80 had very positive effect on the extraction efficiency of dichloromethane (DCM) and acetone. Kinetics of the extraction with the most efficient solvent ethyl acetate showed extraction of capsaicin to follow a pseudo-second order kinetic model. In conclusion, for extraction of capsaicin from green chili, ethyl acetate was the most powerful amongst the solvents used in the present work and tween-80 had a notable positive effect on the efficiency of DCM and acetone.