Rapamycin inhibits hepatitis B virus covalently closed circular DNA transcription by enhancing the ubiquitination of HBx

Hepatitis B virus (HBV) infection is still a serious public health problem worldwide. Antiviral therapies such as interferon and nucleos(t)ide analogs efficiently control HBV replication, but they cannot eradicate chronic hepatitis B (CHB) because of their incapacity to eliminate endocellular covale...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Li, Liang, Cheng, Sheng-Tao, Qin, Yi-Ping, He, Xin, Li, Fan, Wu, Dai-Qing, Ren, Fang, Yu, Hai-Bo, Liu, Jing, Chen, Juan, Ren, Ji-Hua, Zhang, Zhen-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403416/
https://www.ncbi.nlm.nih.gov/pubmed/36033851
http://dx.doi.org/10.3389/fmicb.2022.850087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403416/
https://www.ncbi.nlm.nih.gov/pubmed/36033851
http://dx.doi.org/10.3389/fmicb.2022.850087

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